AI-Driven Investing: Alex Sen & Nnamdi Okike on Transforming Venture Capital and Private Equity

In this episode of the Venture Capital Podcast with hosts Jon Bradshaw and Peter Harris, Alex Sen—CEO & founder of Meridian—joins Nnamdi Okike, Managing Partner and co-founder of 645 Ventures (which led Meridian’s $7M seed round), to unpack how AI-native software is reshaping private equity and venture workflows. Alex shares his journey from nearly a decade in PE fighting legacy CRMs to building Meridian, an AI-powered CRM and thematic sourcing platform. Meridian auto-captures context (emails, meetings, CIMs), surfaces proprietary opportunities, and accelerates conviction. Nnamdi brings the investor side, with a decade of using software and data to scale venture, to tell why AI is expanding the TAM by automating manual tasks and how managers are redefining analyst roles, all while keeping human judgment at the core.

Why listen: Learn how AI changes thematic sourcing, underwriting, and portfolio engagement, where competitive edge is shifting, and the practical side for elevating team capability without losing the human intuition that wins deals.

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